Products
FADD antibody
- SPECIFICATIONS
- CITATIONS
- Product Name
- FADD antibody
- Catalogue No.
- FNab02941
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Fas(TNFRSF6)-associated via death domain
- Alternative Names
- FADD antibody, GIG3 antibody, MORT1 antibody, Protein FADD antibody
- UniProt ID
- Q13158
- Observed MW
- 26 kDa
Application
- Tested Applications
- ELISA, IHC, WB, IP
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab02941(FADD Antibody) at dilution of 1:1000
IP Result of anti-FADD (IP:FNab02941, 4ug; Detection:FNab02941 1:300) with A549 cells lysate 3040ug.
Immunohistochemistry of paraffin-embedded human lung cancer using FNab02941(FADD antibody) at dilution of 1:50
- Background
- Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
IF: 4.092
- Journal:
- The International Journal of Biochemistry & Cell Biology
- Cited Date:
- 2017-11-10
- Product: